Sequences

Child level

Same level

Compiled by: Nick Knowles

Last updated: 05 September, 2008

Family: Astroviridae

Genus: Astrovirus

human astrovirus type 1 (HAstV-1)

human astrovirus type 2 (HAstV-2)

human astrovirus type 3 (HAstV-3)

human astrovirus type 4 (HAstV-4)

human astrovirus type 5 (HAstV-5)

human astrovirus type 6 (HAstV-6)

human astrovirus type 7 (HAstV-7)

human astrovirus type 8 (HAstV-8)

bovine astrovirus 1 (BAstV-1)

bovine astrovirus 2 (BAstV-2)

feline astrovirus (FAstV)

ovine astrovirus 1 (OAstV-1)

porcine astrovirus 1 (PAstV-1)

mink astrovirus 1 (MAstV-1)

duck astrovirus 1 (DAstV-1) (formerly duck hepatitis virus type 2)

turkey astrovirus 1 (TAstV-1)

turkey astrovirus 1 (TAstV-2)

avian nephritis virus 1 (ANV-1)

avian nephritis virus 2 (ANV-2)

Human astrovirus (HAstV) 1-8
Virus	Strain	Region	Length	Accession No.	Reference	Comments
HAstV-1	?	3' terminal sequence RNA	1034	M87668, Z11682	Willcocks and Carter, 1992, 1993
		non-structural	827	Z16420	Willcocks et al., 1991
		CG	6813	S38068; Z25771	Willcocks et al., 1994a
HAstV-1	A88/2 (Newcastle)	capsid	2739	S68561	Willcocks and Carter, 1993
HAstV-1	Oxford	CG	6771	L23513	Lewis et al., 1994
		?	283	L23511	Lewis et al., 1994
		pol(p)	600	L23510	Lewis et al., 1994
HAstV-1	?	immunoreactive protein gene (p)	289	L08015	Matsui et al., 1993
HAstV-1	?	immunoreactive protein gene (p)	434	L08014	Matsui et al., 1993
HAstV-1	?	genome 3' end	118	S47249	Major et al., 1992
HAstV-1	Oxford	RNA polymerase gene (p)	600	L23512	Lewis et al., 1994
HAstV-1	?	outer cp precursor gene	348	U49212	Palombo and Bishop, unpublished
HAstV-1	?	outer cp precursor gene	348	U49213	Palombo and Bishop, unpublished
HAstV-1	?	outer cp precursor gene	348	U49214	Palombo and Bishop, unpublished
HAstV-1	?	outer cp precursor gene	348	U49215	Palombo and Bishop, unpublished
HAstV-1	?	outer cp precursor gene	348	U49216	Palombo and Bishop, unpublished
HAstV-1	?	outer cp precursor gene	348	U49217	Palombo and Bishop, unpublished
HAstV-2	Oxford reference strain	capsid	2484	L06802	Monroe et al., 1993
HAstV-2	Oxford	RNA fragment	283	L23508	Lewis et al., 1994
HAstV-2	Oxford	pol(p)	600	L23509	Lewis et al., 1994
HAstV-2	Oxford	CG	6828	L13745	Jiang et al., 1993
HAstV-3	Oxford reference strain	cp gene	348	L38505	Noel et al., 1995
HAstV-3	Berlin	CG?	6815	AF141381	Schreier and Oh, unpublished
HAstV-3	?	capsid	2478	AF117209	Monroe, S.S. and Stine, S.E., unpublished
HAstV-4	Oxford UK	vp1-3	2396	Z33883	Willcocks and Carter, unpublished
HAstV-4	Oxford reference strain	cp gene	348	L38506	Noel et al., 1995
HAstV-4	?	outer cp precursor gene (p)	348	U49218	Palombo and Bishop, unpublished
HAstV-4	?	outer cp precursor gene (p)	348	U49219	Palombo and Bishop, unpublished
HAstV-5	Oxford reference strain	capsid	2382	U15136	Monroe et al., unpublished
HAstV-5	?	outer cp precursor gene (p)	348	U49220	Palombo and Bishop, unpublished
HAstV-5	Isolate: 96-146, Beijing, China; strain: CHN146	capsid+3'UTR	2514	AB037273	Wang et al., unpublished
HAstV-5	Isolate: 96-198, Beijing, China; strain: CHN198	capsid+3'UTR	2750	AB037274	Wang et al., unpublished
HAstV-6	?	capsid	2418	Z46658	Willcocks et al., 1994b
HAstV-6	Oxford reference strain	capsid (p)	348	L38507	Noel et al., 1995
HAstV-6	?	capsid	2548	AB013618	Oishi et al., 1994
HAstV-6	Katano-23 (K-23)	capsid(p)	357	AB005257	Oishi et al., unpublished
HAstV-7	Oxford reference strain	capsid(p)	348	L38508	Noel et al., 1995
HAstV-7		capsid	2484	Y08632	Monceyron et al., 1997; Jonassen et al., unpub.
HAstV-8	?	orf2 gene for cp	2434	Z66541	Carter et al., unpublished
HAstV-8	Yuc-8	CG	6759	AF260508	Mendez-Toss et al., unpublished
Bovine astrovirus 1 (BAstV-1)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
No sequences available yet
Bovine astrovirus 2 (BAstV-2)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
No sequences available yet
Feline astrovirus (FAstV)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
FAstV	Bristol	capsid protein gene	2511	AF056197	Wilcocks et al., unpublished
Ovine astrovirus 1 (OAstV-1)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
OAstV-1	?	CG	6440	Y15937	Jonassen et al., 1998; Jonassen et al., unpub.
Porcine astrovirus 1 (PAstV-1)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
PAstV-1	Isolate: 83-74, Tokushima, Japan; strain: Tokushima83-74	capsid+3'UTR(p)	2459	Y15938	Jonassen et al., 1998; Jonassen et al., unpub.
PAstV-1	Isolate: 83-74, Tokushima, Japan; strain: Tokushima83-74	capsid+3'UTR	2730	AB037272	Wang et al., unpublished
Mink astrovirus (MAstV)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
MAstV	?	CG	6610	AY179509	Mittelholzer et al., 2003
Turkey astrovirus 1 (TAstV-1)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
TAstV-1	?	CG	7003	Y15936	Jonassen et al., 1998; Jonassen et al., unpub.
Turkey astrovirus 2 (TAstV-2)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
TAstV-2	?	CG	7355	AF206663	Koci et al., 2000	associated with Poult Enteritis Mortality Syndrome
TAstV-2	USA: North Carolina (1988)	ORF2(p)	785	AY320042	Guy et al., unpub.
TAstV-2	USA: North Carolina (1988)	ORF1b(p)	723	AY320043	Guy et al., unpub.
Duck astrovirus 1 (DAstV-1)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
No sequences available yet
Avian nephritis virus 1 (ANV-1)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
ANV-1	G-4260	CG	6927	AB033998	Imada et al., 2000
Avian nephritis virus 2 (ANV-2)
Virus	Strain	Region	Length	Accession No.	Reference	Comments
ANV-2	?	ORF 2 (capsid)	2536	AB046864	Imada et al., unpublished
CG = complete genome; (p) = partial gene sequence

References

Carter, M.J., Willcocks, M.M., Kurtz, J.B. and Lee, T. The sequence of human astrovirus serotype 8. Unpublished.

Guy, J.S., Miles, A., Smith, L.G., Fuller, F. and Schultz-Cherry, S. Antigenic and genomic characterization of Turkey enterovirus-like virus (North Carolina, 1988 isolate) identifies the virus as Turkey astrovirus 2. Unpublished. [College of Vet. Med., North Carolina State Univ., 4700 Hillsborough St., Raleigh, NC 27606, USA]

Imada, T., Yamaguchi, S., Mase, M., Tsukamoto, K., Kubo, M. and Morooka, A. (2000). Avian nephritis virus (ANV) as a new member of the family Astroviridae and construction of infectious ANV cDNA. J. Virol. 74: 8487-8493.

Imada, T., Yamaguchi, S., Mase, M. and Tsukamoto, K. ORF 2 of avian nephritis virus serotype 2 (astrovirus). Unpublished. [Tadao Imada, National Institute of Animal Health, Department of Virology, 3-1-1, Kannondai, Tsukuba, Ibaraki 305-0856, Japan. (E-mail: imadatad@niah.affrc.go.jp, URL: http://ss.niah.affrc.go.jp/NIAH/hoge-s.html, Tel: 81-298-38-7760, Fax:81-298-38-7760)]

Jiang, B., Monroe, S.S., Koonin, E.V., Stine, S.E. and Glass R.I. (1993) RNA sequence of astrovirus: distinctive genomic organization and a putative retrovirus-like ribosomal frameshifting signal that directs the viral replicase synthesis. Proc. Natl. Acad. Sci. U.S.A. 90: 10539-10543.

Jonassen, C.M., Jonassen, T.Ø. and Grinde, B. (1998). A common RNA motif in the 3' end of the genomes of astroviruses, avian infectious bronchitis virus and an equine rhinovirus. J. Gen. Virol. 79: 715-718.

Jonassen, C.M., Jonassen, T., Saif, Y., Snodgrass, D., Ushijima, H., Shimizu, M. and Grinde, B. Comparison of capsid sequences from human and animal astroviruses. Unpublished.

Koci, M.D., Seal, B.S. and Schultz-Cherry, S. (2000). Molecular characterization of an avian astrovirus. J. Virol. 74: 6173-6177.

Lewis, T.L., Greenberg, H.B., Herrmann, J.E., Smith, L.S. and Matsui, S.M. (1994). Analysis of astrovirus serotype 1 RNA, identification of the viral RNA-dependent RNA polymerase motif, and expression of a viral structural protein. J. Virol. 68: 77-83.

Major, M.E., Eglin, R.P. and Easton, A.J. (1992). 3' terminal nucleotide sequence of human astrovirus type 1 and routine detection of astrovirus nucleic acid and antigens. J. Virol. Methods 39:217-225.

Matsui S.M., Kim J.P., Greenberg H.B., Young L.M., Smith L.S., Lewis T.L., Herrmann J.E., Blacklow N.R., Dupuis K. and Reyes G.R. (1993). Cloning and characterization of human astrovirus immunoreactive epitopes. J. Virol. 67: 1712-1715.

Mendez-Toss, M., Romero-Guido, P., Munguia, M.E., Mendez, E. and Arias, C.F. Molecular analysis of a serotype 8 human astrovirus genome. Unpublished. [Genetica y Fisiologia Molecular, Instituto de Biotecnologia/UNAM, Av. Universidad 2001 Col. Chamilpa, Cuernavaca, Mor 62210, Mexico]

Mittelholzer, C., Hedlund, K.-O., Englund, L., Dietz, H.-H. and Svensson, L. (2003). Molecular characterization of a novel astrovirus associated with disease in mink. J. Gen. Virol. 84: 3087-3094.

Monceyron, C., Grinde, B. and Jonassen, T. (1997). Molecular characterization of the 3'-end of the astrovirus genome. Arch. Virol. 142: 699-706.

Monroe S.S., Stine S.E. and Glass R.I. Expression of the major capsid protein from human astrovirus type 5. Unpublished.

Monroe S.S., Jiang B., Stine S.E., Koopmans M. and Glass R.I. (1993). Subgenomic RNA sequence of human astrovirus supports classification of Astroviridae as a new family of RNA viruses. J. Virol. 67: 3611-3614.

Noel, J.S., Lee, T.W., Kurtz, J.B., Glass, R.I. and Monroe S.S. (1995). Typing of human astroviruses from clinical isolates by enzyme immunoassay and nucleotide sequencing. J. Clin. Microbiol. 33: 797-801.

Oishi, I., Yamazaki, K., Utagawa, E., Yamazaki, S., Inouye, S., Grohmann, G.s., Monroe, S.S., Stine, S.E., Ando, T. and Glass, R.I. (1994). A large outbreak of acute gastroenteritis associated with astrovirus among students and teachers in Osaka, Japan. J. Infect. Dis. 170: 439-443.

Oishi, I., Yamazaki, K., Kase, T., Kimoto, T., Sakon, N., Utagawa, E., Okuno, Y., Ando, T. and Glass, R. The clinical features and genomic sequence analysis of the causative agent, Katano virus of human astrovirus type 6, isolated from outbreak of gastroenteritis in Japan. Unpublished, [Osaka Prefectural Institute of Public Health, Laboratory of Pathology; Nakamichi 1-chome Higashinari-ku, Osaka 537-0025, Japan; E-mail: ooisi@iph.pref.osaka.jp; Tel:81-6-972-1321; Fax:81-6-972-2393]

Palombo, E.A. and Bishop R.F. Sequence analysis of astrovirus clinical isolates. Unpublished.

Schreier, E. and Oh, D.I. Molecular characterization of human astrovirus serotype 3. Unpublished. [Molecular Virology, Robert Koch Institute, Nordufer 20, Berlin 13353, Germany]

Wang, Q., Ushijima, H. and Shimizu, M. Genetic analysis of the capsid region of astroviruses. Unpublished. [Hiroshi Ushijima, Graduate School of Medicine, The University of Medicine, Department of Developmental Medical Sciences; Hongo 7-3-1,Bunkyo-ku, Tokyo 113-0033, Japan (E-mail: ushijima@m.u-tokyo.ac.jp, Tel:+81-3-5841-3629, Fax:+81-3-5841-3629)]

Willcocks M.M. and Carter M.J. (1992). The 3' terminal sequence of a human astrovirus. Arch. Virol. 124: 279-289.

Willcocks M.M. and Carter M.J. (1993). Identification and sequence determination of the capsid protein gene of human astrovirus serotype 1. FEMS Microbiol. Lett. 114: 1-7.

Willcocks M.M. and Carter M.J. The structural protein of a human astrovirus serotype 4. Unpublished.

Wilcocks, M.M., Carter, M.J. and Harbour D.A. Feline astrovirus capsid sequence and relatedness to human strains. Unpublished.

Willcocks M.M., Carter M.J., Silcock J.G. and Madeley C.R. (1991). A dot-blot hybridisation procedure for the detection of astrovirus in stool samples. Epidemiol. Infect. 107: 405-410.

Willcocks M.M., Brown T.O.K., Maddey C.R. and Carter M.J. (1994a). The complete sequence of a Human Astrovirus. J. Gen. Virol. 75: 1785-1788.

Willcocks M.M., Kurtz J.B., Lee T.W. and Carter M.J. (1994b). Prevalence of human astrovirus serotype 4: capsid protein sequence and comparison with other strains. Epidemiol. Infect. 0:0-0.

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